DCK

BT-AP02174

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human DCK

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely| increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

Human: P27707; Mouse: P43346; Rat: P48769;

28600

Human: 1633; Mouse: 13178; Rat: 79127

DCK

Cancer; Signal transduction

DCK