DNA pol beta

BT-AP02275

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human DNA pol β (Acetyl Lys72)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).|cofactor:Binds 2 magnesium ions per subunit.|Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.|Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.|PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.|Belongs to the DNA polymerase type-X family.|subunit:Monomer.|

Human: P06746; Mouse: Q8K409; Rat: P06766;

36850

Human: 5423; Mouse: 18970; Rat: 29240

DNA pol β ;Acetyl Lys72; DNA polymerase beta; EC 2.7.7.7; EC 4.2.99.-

Epigenetics and nuclear signaling

POLB