DNAJC2

BT-AP09271

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human DNAJC2 and MPP11 (Ser47)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes| acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also| chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

Human: Q99543; Mouse: P54103; Rat: Q7TQ20;

Human: 27000; Mouse: 22791; Rat: 116456

DNAJC2/MPP11 ;Ser47; DnaJ homolog subfamily C member 2; M-phase phosphoprotein 11; Zuotin-related factor 1

Cancer; Signal transduction

DNAJC2