DR6

BT-AP02307

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human DR6 (Ser562)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1)| and induces cell apoptosis. Through its death domain| the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein| which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation| and may be involved in inflammation and immune regulation.

Human: O75509; Mouse: Q9EPU5;

Human: 27242; Mouse: 94185

DR6 ;Ser562; Tumor necrosis factor receptor superfamily member 21; Death receptor 6; CD antigen CD358

Cell biology

TNFRSF21