DSE

BT-AP09343

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human DSE

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.249% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9| and a paralogous gene exists on chromosome 18.

Human: Q9UL01; Mouse: Q8BLI4;

Human: 29940; Mouse: 212898

DSE; Dermatan-sulfate epimerase; DS epimerase; EC 5.1.3.19; Chondroitin-glucuronate 5-epimerase; Squamous cell carcinoma antigen recognized by T-cells 2; SART-2)

Metabolism

DSE