DUOX1

BT-AP02326

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human DUOX1

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter| thyroperoxidase| and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase| lactoperoxidase| and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Human: Q9NRD9; Rat: Q8CIY2;

170610

Human: 53905; Rat: 266807

DUOX1

Metabolism; Neuroscience; Signal transduction

DUOX1