DYL1

BT-AP09379

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human DYL1

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1|200 kD. They contain two force-producing heads formed primarily from dynein heavy chains| and stalks linking the heads to a basal domain| which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer| a conformation necessary for activity| and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.

Human: P63167; Mouse: P63168; Rat: P63170;

9790

Human: 8655; Mouse: 56455; Rat: 58945

DYL1

Cancer; Cell biology; Epigenetics and nuclear signaling; Metabolism; Neuroscience; Signal transduction

DYNLL1