EST1

BT-AP09762

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human EST1

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.142% sodium azide.

-20°C for 1 year

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics| such as cocaine and heroin| and endogenous substrates with ester| thioester| or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism| and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Human: P23141; Mouse: Q8VCC2;

Human: 1066; Mouse: 12623

EST1; Liver carboxylesterase 1; Acyl-coenzyme A:cholesterol acyltransferase; ACAT; Brain carboxylesterase hBr1; Carboxylesterase 1; CE-1; hCE-1; EC 3.1.1.1; Cocaine carboxylesterase; Egasyn; HMSE; Methylumbelliferyl-acetate deacetylase 1; EC 3.1.1.56; Monocyte/macrophage serine esterase; Retinyl ester hydrolase; REH; Serine esterase 1; Triacylglycerol hydrolase; TGH)

Cardiovascular; Metabolism; Signal transduction

CES1