FA9

BT-AP09977

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human FA9 (light chain| Cleaved-Tyr47)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa| which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions| membrane phospholipids| and factor VIII. Alterations of this gene| including point mutations| insertions and deletions| cause factor IX deficiency| which is a recessive X-linked disorder| also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

Human: P00740; Mouse: P16294; Rat: P16296;

50710

Human: 2158; Mouse: 14071; Rat: 24946

FA9 ;light chain; Cleaved-Tyr47; Coagulation factor IX; EC 3.4.21.22; Christmas factor; Plasma thromboplastin component; PTC; Coagulation factor IXa light chain; Coagulation factor IXa heavy chain;

Cardiovascular; Immunology

F9