FGF Receptor

BT-AP10034

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human FGF Receptor (Tyr653 and 654)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family| where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors| setting in motion a cascade of downstream signals| ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome| Jackson-Weiss syndrome|

Human: P11362; Mouse: P16092; Rat: Q04589;

Human: 2260; Mouse: 14182; Rat: 79114

FGF Receptor ;Tyr653/654; Fibroblast growth factor receptor 1; FGFR-1; EC 2.7.10.1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R-1; Fms-like tyrosine kinase 2; FLT-2; N-sam; Proto-oncogene c-Fgr; CD antigen CD331

Cancer; Cardiovascular; Signal transduction; Microbiology; Neuroscience

FGFR1