HEM1

BT-AP02957

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human HEM1

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.

Human: P13196; Mouse: Q8VC19; Rat: P13195;

70400

Human: 211; Mouse: 11655; Rat: 65155

HEM1

Cardiovascular; Metabolism; Signal transduction

ALAS1