HNF1alpha

BT-AP03026

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human HNF1α (Ser247)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.

Human: P20823; Mouse: P22361; Rat: P15257;

Human: 6927; Mouse: 21405; Rat: 24817

HNF1α ;Ser247; Hepatocyte nuclear factor 1-alpha; HNF-1-alpha; HNF-1A; Liver-specific transcription factor LF-B1; LFB1; Transcription factor 1; TCF-1

Epigenetics and nuclear signaling

HNF1A