ITGAE

BT-AP10703

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human ITGAE (light chain| Cleaved-Arg177)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain| yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin| this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL)| and in addition to a role in adhesion| it may serve as an accessory molecule for IEL activation.

Human: P38570; Mouse: Q60677;

129690

Human: 3682; Mouse: 16407

ITGAE ;light chain; Cleaved-Arg177; Integrin alpha-E; HML-1 antigen; Integrin alpha-IEL; Mucosal lymphocyte 1 antigen; CD antigen CD103; Integrin alpha-E light chain; Integrin alpha-E heavy chain;

Immunology; Signal transduction; Stem cells; Epigenetics and nuclear signaling

ITGAE