ITGAV

BT-AP03164

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human ITGAV (light chain| Cleaved-Asp891)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1| beta 3| beta 5| beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Human: P06756; Mouse: P43406;

115280

Human: 3685; Mouse: 16410

ITGAV ;light chain; Cleaved-Asp891; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51; Integrin alpha-V heavy chain; Integrin alpha-V light chain;

Cardiovascular; Stem cells; Microbiology; Signal transduction; Immunology; Cancer

ITGAV