LCP1

BT-AP03394

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human LCP1 (Tyr28)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans| two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages| while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts| endothelial cells| epithelial cells| melanocytes| etc.). However| L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.

Human: P13796; Mouse: Q61233;

Human: 3936; Mouse: 18826

LCP1 ;Tyr28; Plastin-2; L-plastin; LC64P; Lymphocyte cytosolic protein 1; LCP-1

Cancer; Signal transduction ; Epigenetics and nuclear signaling

LCP1