LIS1

BT-AP03417

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human LIS1

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase| a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits| the other| a single subunit. In addition| a single-subunit isoform of this enzyme is found in serum.

Human: P43034; Mouse: P63005; Rat: P63004;

45100

Human: 5048; Mouse: 18472; Rat: 83572

LIS1

Neuroscience

PAFAH1B1