LONM

BT-AP11093

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human LONM

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.251% sodium azide.

-20°C for 1 year

This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded| unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes| and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene.

Human: P36776; Mouse: Q8CGK3; Rat: Q924S5;

Human: 9361; Mouse: 74142; Rat: 170916

LONM; Lon protease homolog; mitochondrial; EC 3.4.21.-; LONHs; Lon protease-like protein; LONP; Mitochondrial ATP-dependent protease Lon; Serine protease 15

Cancer; Epigenetics and nuclear signaling; Metabolism

LONP1