LOXL4

BT-AP11100

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human LOXL4

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue| encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity| suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation| senescence| tumor suppression| cell growth control| and chemotaxis to each member of the family.

Human: Q96JB6; Mouse: Q924C6;

83160

Human: 84171; Mouse: 67573

LOXL4

Cancer; Signal transduction

LOXL4