LRP5

BT-AP11137

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human LRP5

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.

Human: O75197; Mouse: Q91VN0;

177650

Human: 4041; Mouse: 16973

LRP5

Cardiovascular; Metabolism; Neuroscience ; Signal transduction; Stem cells

LRP5