MAX

BT-AP03544

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human MAX (Phospho Ser11)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members| which include Mad| Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation| differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Human: P61244; Mouse: P28574; Rat: P52164;

17600

Human: 4149; Mouse: 0; Rat: 60661

MAX ;Phospho Ser11; Protein max; Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X

Epigenetics and nuclear signaling

MAX