MKKS

BT-AP11334

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human MKKS

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.184% sodium azide.

-20°C for 1 year

This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome| which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified| which repress the translation of the dORF| and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6| also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants.

Human: Q9NPJ1; Mouse: Q9JI70;

Human: 8195; Mouse: 59030

MKKS; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; Bardet-Biedl syndrome 6 protein

Metabolism; Epigenetics and nuclear signaling

MKKS