MYPT1/2

BT-AP11475

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human MYPT1/2 (Phospho Ser668/Ser618)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Regulates myosin phosphatase activity.|PTM:Phosphorylated by CIT (Rho-associated kinase) (By similarity). Phosphorylated cooperatively by ROCK1 and CDC42BP on Thr-696. Phosphorylated on upon DNA damage| probably by ATM or ATR.|sequence Contaminating sequence. Potential poly-A sequence.|Contains 6 ANK repeats.|subcellular location:Along actomyosin filaments and stress fibers.|subunit:PP1 comprises a catalytic subunit| PPP1CA| PPP1CB or PPP1CC| and one or several targeting or regulatory subunits. PPP1R12A mediates binding to myosin. Interacts with ARHA and CIT (By similarity). Binds PPP1R12B| ROCK1 and IL16.|

Human: O14974/O60237; Mouse: Q9DBR7; Rat: Q10728;

113300

Human: 4659; Mouse: 17931; Rat: 116670

MYPT1/2 ;Phospho Ser668/Ser618; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit

Epigenetics and nuclear signaling; Signal transduction

PPP1R12A