NEDD4

BT-AP11511

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human NEDD4

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and| a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors| endocytic machinery components and the tumor suppressor PTEN.

Human: P46934; Mouse: P46935; Rat: Q62940;

145090

Human: 4734; Mouse: 17999; Rat: 25489

NEDD4

Cell biology; Epigenetics and nuclear signaling; Neuroscience

NEDD4