Cellular tumor antigen p53

BT-AP11724

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthetic Peptide of p53

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

-20°C for 1 year

This gene encodes a tumor suppressor protein containing transcriptional activation| DNA binding| and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes| thereby inducing cell cycle arrest| apoptosis| senescence| DNA repair| or changes in metabolism. Mutations in this gene are associated with a variety of human cancers| including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546| 20937277).

Human: P04637; Mouse: P02340; Rat: P10361;

Human: 7157

Cellular tumor antigen p53; TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

Epigenetics and nuclear signaling; Cancer; Cell biology

TP53