p70 S6 Kinase

BT-AP11747

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human p70 S6 Kinase (Thr389)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis| cell growth| and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Human: P23443; Mouse: Q8BSK8; Rat: P67999;

Human: 6198; Mouse: 72508; Rat: 83840

p70 S6 Kinase ;Thr389 ; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; EC 2.7.11.1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA

Cell biology; Epigenetics and nuclear signaling; Metabolism; Signal transduction

RPS6KB1