PAX6

BT-AP11794

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human PAX6

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues| particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.

Human: P26367; Mouse: P63015; Rat: P63016;

46420

Human: 5080; Mouse: 18508; Rat: 25509

PAX6; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin

Developmental biology; Epigenetics and nuclear signaling; Neuroscience; Stem cells

PAX6