PDE11

BT-AP11851

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human PDE11

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The 3'|5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3'|5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

Human: Q9HCR9; Mouse: P0C1Q2; Rat: Q8VID6;

102630

Human: 50940; Mouse: 241489; Rat: 140928

PDE11

Signal transduction

PDE11A