PPAR alpha

BT-AP12079

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human PPAR α (Phospho Ser21)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand| the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.|online information:Peroxisome proliferator-activated receptor entry|Belongs to the nuclear hormone receptor family. NR1 subfamily.|Contains 1 nuclear receptor DNA-binding domain.|subunit:Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators| leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13.|tissue specificity:Skeletal muscle| liver| heart and kidney.|

Human: Q07869; Mouse: P23204; Rat: P37230;

51480

Human: 5465; Mouse: 19013; Rat: 25747

PPAR α ;Phospho Ser21; Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1

Cancer; Cardiovascular; Epigenetics and nuclear signaling; Metabolism

PPARA