PSB10

BT-AP12199

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human PSB10

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome| the immunoproteasome| is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family| also known as the T1B family| that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon| and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.

Human: P40306; Mouse: O35955; Rat: Q4KM35;

30030

Human: 5699; Mouse: 19171; Rat: 291983

PSB10

Cell biology; Immunology

PSMB10