Rad18

BT-AP12227

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human Rad18 (Ser403)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6| which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart| this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

Human: Q9NS91; Mouse: Q9QXK2;

Human: 56852; Mouse: 58186

Rad18 ;Ser403 ; E3 ubiquitin-protein ligase RAD18; EC 6.3.2.-; Postreplication repair protein RAD18; hHR18; hRAD18; RING finger protein 73

Cell biology; Epigenetics and nuclear signaling

RAD18