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Home > Product > Antibody > Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody

Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody

Rb(Phospho-Ser807/811) Rabbit Polyclonal Antibody

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB

Product Summary

Size: 100ul,50ul,20ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

Product overview

Full product name

Rb

Code

BT-AP12238

Host

Rabbit

Isotype

IgG

Size

100ul,50ul,20ul

Clonality

Polyclonal

Immunogen

Synthesized phosho peptide around human Rb (Ser807 and 811)

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active| hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB)| bladder cancer| and osteogenic sarcoma.

Uniprot accession

Gene ID

Human: 5925; Mouse: 19645; Rat: 24708

Synonyms

Rb ;Ser807/811 ; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110

Research area

Cancer; Cell biology; Epigenetics and nuclear signaling

Target protein

RB1

Recommended dilution

Application Dilution
WB 1: 1000 - 1: 2000

Protocols

References

Customer reviews and Q&As

No reviews
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Product size

Price

  • 100ul

    $275.00

  • 50ul

    $180.00

  • 20ul

    $108.00

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Lead time: Within one week

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