RN103

BT-AP04493

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human RN103

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene contains a RING-H2 finger| a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum| but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment| suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene.

Human: O00237; Mouse: Q9R1W3; Rat: Q9EPZ8;

75350

Human: 7844; Mouse: 22644

RN103

Epigenetics and nuclear signaling

RNF103