SF3B1

BT-AP04709

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human SF3B1 (Thr313)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b| together with splicing factor 3a and a 12S RNA unit| forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical| tandem HEAT repeats that form rod-like| helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.

Human: O75533; Mouse: Q99NB9;

Human: 23451

SF3B1 ;Thr313 ; Splicing factor 3B subunit 1; Pre-mRNA-splicing factor SF3b 155 kDa subunit; SF3b155; Spliceosome-associated protein 155; SAP 155

Epigenetics and nuclear signaling

SF3B1