SNX13

BT-AP12702

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human SNX13

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.277% sodium azide.

-20°C for 1 year

This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain| and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s)| accelerates its GTP hydrolysis| and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role| this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Human: Q9Y5W8; Mouse: Q6PHS6;

Human: 23161; Mouse: 217463

SNX13; Sorting nexin-13; RGS domain- and PHOX domain-containing protein; RGS-PX1

Signal transduction

SNX13