SSRP1

BT-AP04909

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human SSRP1

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a subunit of a heterodimer that| along with SUPT16H| forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described| but its full-length nature is not known.

Human: Q08945; Mouse: Q08943; Rat: Q04931;

77990

Human: 6749; Mouse: 20833; Rat: 81785

SSRP1

Epigenetics and nuclear signaling

SSRP1