TBK1/NAK

BT-AP12986

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human TBK1 and NAK (Ser172)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins| which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway| thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

Human: Q9UHD2; Mouse: Q9WUN2;

Human: 29110; Mouse: 56480

TBK1/NAK ;Ser172 ; Serine/threonine-protein kinase TBK1; EC 2.7.11.1; NF-kappa-B-activating kinase; T2K; TANK-binding kinase 1

Epigenetics and nuclear signaling; Signal transduction

TBK1