TNK1

BT-AP13110

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human TNK1 (Tyr277)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways| mediating cellular proliferation| survival| and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues| thus may function in signaling pathways utilized broadly during fetal development| and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway| and knockout mice have been shown to develop spontaneous tumors| suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Human: Q13470; Mouse: Q99ML2;

Human: 8711; Mouse: 83813

TNK1 ;Tyr277 ; Non-receptor tyrosine-protein kinase TNK1; EC 2.7.10.2; CD38 negative kinase 1

Signal transduction; Cancer; Cell biology

TNK1