Tyk2

BT-AP13304

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized phosho peptide around human Tyk2 (Tyr1054 and 1055)

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the tyrosine kinase and| more specifically| the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such| it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

Human: P29597; Mouse: Q9R117;

Human: 7297

Tyk2 ;Tyr1054/1055 ; Non-receptor tyrosine-protein kinase TYK2; EC 2.7.10.2

Signal transduction; Microbiology

TYK2