UN13B

BT-AP13373

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human UN13B

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog| and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol| which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.

Human: O14795; Mouse: Q9Z1N9; Rat: Q62769;

175010

Human: 10497; Mouse: 22249; Rat: 64830

UN13B

Neuroscience

UNC13B