ATP-binding cassette sub-family A member 1

BT-AP13983

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1| MDR/TAP| MRP| ALD| OABP| GCN20| White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate| this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

Human: O95477; Mouse: P41233;

Human: 19

ATP-binding cassette sub-family A member 1 ;ATP-binding cassette transporter 1;ABC-1;ATP-binding cassette 1;Cholesterol efflux regulatory protein

Cancer; Cardiovascular; Metabolism; Neuroscience; Signal transduction

ABCA1