Long-chain-fatty-acid--CoA ligase 5

BT-AP06019

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 460-540

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity| subcellular localization| and tissue distribution| all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters| and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen| and in trace amounts in normal brain| but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

Human: Q9ULC5; Mouse: Q8JZR0; Rat: O88813;

Human: 51703

Long-chain-fatty-acid--CoA ligase 5 ;EC 6.2.1.3;Long-chain acyl-CoA synthetase 5;LACS 5

Signal transduction

ACSL5