Disintegrin and metalloproteinase domain-containing protein 22

BT-AP14128

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins| and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions| including fertilization| muscle development| and neurogenesis. Unlike other members of the ADAM protein family| the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice| it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

Human: Q9P0K1; Mouse: Q9R1V6;

Human: 53616

Disintegrin and metalloproteinase domain-containing protein 22 ;ADAM 22;Metalloproteinase-disintegrin ADAM22-3;Metalloproteinase-like; disintegrin-like; and cysteine-rich protein 2

Signal transduction; Cell biology

ADAM22