Peptidyl-glycine alpha-amidating monooxygenase

BT-AP14196

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 380-460

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Human: P19021; Mouse: P97467; Rat: P14925;

Human: 5066

Peptidyl-glycine alpha-amidating monooxygenase ;PAM [Includes: Peptidylglycine alpha-hydroxylating monooxygenase ;PHM;EC 1.14.17.3; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase ;EC 4.3.2.5

Neuroscience; Signal transduction

PAM