Atrial natriuretic peptide receptor 2

BT-AP06287

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Human: P20594; Mouse: Q6VVW5; Rat: P16067;

Human: 4882

Atrial natriuretic peptide receptor 2 ;EC 4.6.1.2;Atrial natriuretic peptide receptor type B;ANP-B;ANPR-B;NPR-B;Guanylate cyclase B;GC-B

Cardiovascular; Neuroscience; Signal transduction

NPR2