Beta-adrenergic receptor kinase 1

BT-AP14299

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 1-80

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

Human: P25098; Mouse: Q99MK8; Rat: P26817;

Human: 156

Beta-adrenergic receptor kinase 1 ;Beta-ARK-1;EC 2.7.11.15;G-protein coupled receptor kinase 2

Neuroscience; Signal transduction

ADRBK1