Full product name
Beclin-1
Code
BT-AP14447
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Beclin-1 . at AA range: 110-190
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
Uniprot accession
Molecular weight
51896
Gene ID
Human: 8678; Mouse: 56208
Synonyms
Beclin-1; beclin 1, autophagy related
Research area
Cancer; Epigenetics and nuclear signaling; Metabolism; Microbiology
Target protein
BECN1
