Bestrophin-1

BT-AP14451

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthetic Peptide of Bestrophin-1

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Human: O76090; Mouse: O88870;

Human: 7439

Bestrophin-1 ;TU15B;Vitelliform macular dystrophy protein 2; Bestrophin-1; TU15B; Vitelliform macular dystrophy protein 2

Neuroscience

BEST1