Cytochrome P450 11B2, mitochondrial

BT-AP06943

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 280-360

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Human: P19099; Mouse: P15539; Rat: P30099;

Human: 1585

Cytochrome P450 11B2, mitochondrial ;Aldosterone synthase;ALDOS;EC 1.14.15.4;EC 1.14.15.5;Aldosterone-synthesizing enzyme;CYPXIB2;Cytochrome P-450Aldo;Cytochrome P-450C18;Steroid 18-hy

Cardiovascular; Metabolism

CYP11B2