CD2-associated protein

BT-AP07362

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 320-400

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Human: Q9Y5K6; Mouse: Q9JLQ0;

Human: 23607

CD2-associated protein ;Adapter protein CMS;Cas ligand with multiple SH3 domains

Signal transduction

CD2AP