Cytochrome P450 2C9

BT-AP08039

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Human: P11712;

Human: 1559

Cytochrome P450 2C9 ;EC 1.14.13.-;;R-limonene 6-monooxygenase;EC 1.14.13.80;;S-limonene 6-monooxygenase;EC 1.14.13.48;;S-limonene 7-monooxygenase;EC 1.14.13.49;CYPIIC9;Cytochrome P-

Cardiovascular; Metabolism; Signal transduction

CYP2C9